SCHEMBL463653

SCHEMBL463653

COC(=O)N1C(=O)CCC1=O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 2/20 0.39
BCHE P06276 1/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
BRD4 O60885 2/20 0.35
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
USP2 O75604 1/20 0.34
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 2/20 0.33
GLA P06280 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33
POLB P06746 1/20 0.33
LPO P22079 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11579499 0.91 P2RX4 (0.37) P2RX4BCHETSHRMEN1KMT2A
SCHEMBL14363762 0.79 GLA (0.31) GLAPOLB
SCHEMBL19450052 0.78 GLA (0.30) GLA
SCHEMBL9546782 0.78 BRD4 (0.37) TSHRMEN1KMT2ABRD4ALDH1A1
SCHEMBL383890 0.77 GLA (0.31) GLA
SCHEMBL23733088 0.76 BRD4 (0.33) KMT2ABRD4ALDH1A1HPGDUSP2
SCHEMBL5573133 0.76 ALDH1A1 (0.44) BCHETSHRMEN1KMT2AALDH1A1
SCHEMBL933434 0.75 MGLL (0.32) KMT2A
SCHEMBL7441835 0.75 MGLL (0.32)
SCHEMBL3748240 0.75 BCHE (0.43) BCHEUSP2SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930872-A Catalyst system, prepolymerized catalyst composition and olefin polymerization process 中国石油化工股份有限公司 2025-05-06 CN claimed
WO-2016147132-A1 A PROCESS FOR THE PREPARATION OF DROXIDOPA Piramal Enterprises Limited (IN) 2016-09-22 WO claimed
US-4224441-A Derivatives of 7-aminocephalosporanic acid TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1980-09-23 US claimed
US-4166178-A 3-ACYLOXYMETHYL-CEPHEM COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1979-08-28 US claimed
CN-120040543-A Thymus targeting peptidyl ionizable lipids and nanoparticles thereof 中国科学院动物研究所 2025-05-27 CN disclosed
CN-119930872-A Catalyst system, prepolymerized catalyst composition and olefin polymerization process 中国石油化工股份有限公司 2025-05-06 CN disclosed
US-20250108123-A1 COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2025-04-03 US disclosed
CN-222131935-U Benzyloxy (BYO) carbonyl succinyl dehydration reaction device for imine production 四川安派博生物科技有限公司 2024-12-10 CN disclosed
CN-222131935-U Benzyloxy (BYO) carbonyl succinyl dehydration reaction device for imine production 四川安派博生物科技有限公司 2024-12-10 CN disclosed
CN-118883784-A Melilotoin besylate method for detecting pregabalin 苏州正济药业有限公司 2024-11-01 CN disclosed
CN-118624792-A Pretreatment method of organic matter sample and detection method of lysine substances 首都医科大学 2024-09-10 CN disclosed
CN-221132268-U Reaction kettle for synthesizing fluorenylmethoxycarbonyl succinimide 四川安派博生物科技有限公司 2024-06-14 CN disclosed
US-5024994-A Hypotensive agents WARNER-LAMBERT COMPANY (US) 1991-06-18 US disclosed
EP-0275480-A2 Renin inhibitors IV WARNER-LAMBERT COMPANY (US) 1988-07-27 EP disclosed
US-4608420-A SELF-CURING OR CURING AGENTS FOR HYDROXY COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1986-08-26 US disclosed
US-4224441-A Derivatives of 7-aminocephalosporanic acid TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1980-09-23 US disclosed
US-4166178-A 3-ACYLOXYMETHYL-CEPHEM COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1979-08-28 US disclosed
US-4120809-A Washing and bleaching with composition containing bleach activator and a nitrilotricarboxylic acid compound COLGATE-PALMOLIVE COMPANY (US) 1978-10-17 US disclosed
US-3982891-A Bleaching and detergent compositions having imide activator and peroxygen bleach COLGATE-PALMOLIVE COMPANY (US) 1976-09-28 US disclosed
US-3969257-A Washing and bleaching composition containing bleach, activator and a nitrilotricarboxylic acid compound COLGATE-PALMOLIVE COMPANY (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250108123-A1 COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF STING1, IRF3, CGAS P2RX4 935/4885BCHE 3926/4885TSHR 2958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.