Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899294 | 1.00 | ESR1 (0.48) | ESR1SMN1; SMN2LMNAADORA3ATM | |
| SCHEMBL2832843 | 1.00 | ESR1 (0.48) | ESR1SMN1; SMN2LMNAADORA3ATM | |
| SCHEMBL7707677 | 1.00 | ESR1 (0.48) | ESR1SMN1; SMN2LMNAADORA3ATM | |
| SCHEMBL4281671 | 0.82 | ESR1 (0.63) | ESR1SMN1; SMN2LMNAPGRAR | |
| SCHEMBL2835305 | 0.82 | ESR1 (0.63) | ESR1SMN1; SMN2LMNAPGRAR | |
| SCHEMBL6899123 | 0.82 | ESR1 (0.63) | ESR1SMN1; SMN2LMNAPGRAR | |
| SCHEMBL1246985 | 0.82 | LMNA (0.67) | ESR1SMN1; SMN2LMNAADORA3ATM | |
| SCHEMBL4284331 | 0.82 | LMNA (0.67) | ESR1SMN1; SMN2LMNAADORA3ATM | |
| SCHEMBL7704864 | 0.81 | ESR1 (0.45) | ESR1SMN1; SMN2LMNAADORA3ATM | |
| SCHEMBL2838358 | 0.81 | HSD17B1 (0.47) | ESR1SMN1; SMN2LMNAADORA3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6352980-B1 | ADMINISTERING BY SPRAYING IN NOSE | PHERIN PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | claimed |
| US-5939570-A | Estrenes for inducing hypothalamic effects | PHERIN CORPORATION (US) | 1999-08-17 | — | — | US | claimed |
| EP-0924219-A2 | Novel estrenes for inducing hypothalamic effects | PHERIN CORPORATION (US) | 1999-06-23 | — | — | EP | claimed |
| US-20100111896-A1 | Items Containing A Human Pheromone Component | MARENBERG BARRY J | 2010-05-06 | — | — | US | disclosed |
| US-6352980-B1 | ADMINISTERING BY SPRAYING IN NOSE | PHERIN PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | disclosed |
| US-5994568-A | BIND TO NEUROEPITHELIAL RECEPTORS. | PHERIN CORPORATION (US) | 1999-11-30 | — | — | US | disclosed |
| US-5939570-A | Estrenes for inducing hypothalamic effects | PHERIN CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5925774-A | ESTRENE STEROIDS WHICH BIND TO NEUROEPITHELIAL RECEPTORS | PHERIN CORPORATION (US) | 1999-07-20 | — | — | US | disclosed |
| EP-0924219-A2 | Novel estrenes for inducing hypothalamic effects | PHERIN CORPORATION (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5633392-A | STIMULANTS FOR AUTONOMIC NERVOUS SYSTEM; NOSE SPRAYING | PHERIN CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |