Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CDC42 | P60953 | 1/20 | 0.46 |
| ▸ | RAC1 | P63000 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490635 | 0.88 | PTGS2 (0.57) | PTGS2PTGS1AKR1C3AKR1C2CDC42 | |
| SCHEMBL30946604 | 0.88 | PTGS2 (0.57) | PTGS2PTGS1AKR1C3AKR1C2CDC42 | |
| SCHEMBL2398222 | 0.86 | TP53 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28027161 | 0.86 | ADRA1A (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27546842 | 0.84 | GPR88 (0.47) | TP53KMT2AMEN1 | |
| SCHEMBL8639782 | 0.83 | NPC1 (0.54) | CA1CA2TP53NPC1ALDH1A1 | |
| SCHEMBL491096 | 0.82 | HIF1A (0.46) | TP53ALDH1A1MAPTTSHR | |
| SCHEMBL28162836 | 0.82 | NPC1 (0.53) | NPC1PTGS2ALDH1A1PTGS1AKR1C3 | |
| SCHEMBL28757453 | 0.81 | LPAR1 (0.47) | LPAR1ALDH1A1MAPTCYP1A2TSHR | |
| SCHEMBL27974415 | 0.81 | PTGS2 (0.45) | PTGS2PTGS1AKR1C3AKR1C2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483258-A | Diaryl derivative compound and skin lightening compositions comprising the compound | AMOREPACIFIC CORP | 2019-11-22 | — | — | CN | disclosed |