Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9396711 | 0.80 | PKM (0.67) | NPC1L3MBTL1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL1367369 | 0.79 | NPC1 (0.71) | NPC1L3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4703791 | 0.79 | NPC1 (0.61) | NPC1L3MBTL1RAB9AALDH1A1HPGD | |
| SCHEMBL995011 | 0.78 | NPC1 (0.69) | NPC1L3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2430838 | 0.78 | NPC1 (0.59) | NPC1L3MBTL1RAB9AALDH1A1HPGD | |
| SCHEMBL1703491 | 0.77 | LMNA (0.49) | NPC1L3MBTL1RAB9AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL28690898 | 0.77 | SCN1A (0.61) | NPC1L3MBTL1RAB9AALDH1A1HPGD | |
| SCHEMBL24131812 | 0.77 | NPC1 (0.63) | NPC1L3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16760967 | 0.77 | MAPK8 (0.66) | NPC1L3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4788237 | 0.76 | L3MBTL1 (0.70) | NPC1L3MBTL1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106699724-B | A method of recycling articaine hydrochloride or in which product from synthesis mother liquid | 蚌埠丰原涂山制药有限公司 | 2019-10-25 | — | — | CN | disclosed |