Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | FRK | P42685 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1079285 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL15150212 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL18235389 | 0.71 | MAP4K4 (0.41) | ALDH1A1TDP1MAP4K4MEN1KMT2A | |
| SCHEMBL21787714 | 0.68 | MPO (0.36) | ALDH1A1TDP1MAP4K4EGFRFRK | |
| SCHEMBL6305075 | 0.68 | KDM4E (0.38) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL15880359 | 0.67 | ALDH1A1 (0.40) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1082035 | 0.67 | ALDH1A1 (0.40) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL24915251 | 0.66 | IRAK4 (0.35) | ALDH1A1MAP4K4EGFRFRKMAPK9 | |
| SCHEMBL13242164 | 0.66 | THRB (0.40) | ALDH1A1MAP4K4EGFRFRKMAPK9 | |
| SCHEMBL1859454 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110506043-A | COMPOUNDS USEFUL AS RET INHIBITORS | CANCER RES TECH LIMITED | 2019-11-26 | — | — | CN | disclosed |