Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21639588 | 0.88 | CA1 (0.58) | CA1CA2HIF1AAPLNRKDM4C | |
| SCHEMBL21639656 | 0.82 | CA1 (0.72) | CA1CA2HIF1AAPLNRKDM4C | |
| SCHEMBL28332205 | 0.80 | KDM4C (0.51) | HIF1AAPLNRKDM4CCYP1A2CYP3A4 | |
| SCHEMBL27948920 | 0.78 | APLNR (0.69) | HIF1AAPLNRDHFRALDH1A1HSD17B10 | |
| SCHEMBL20132420 | 0.77 | CA1 (0.76) | CA1CA2HIF1AALDH1A1USP2 | |
| SCHEMBL468287 | 0.75 | HSD17B10 (0.65) | CA1CA2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL15400259 | 0.73 | APLNR (0.61) | HIF1AAPLNRDHFRCYP1A2CYP3A4 | |
| SCHEMBL11983159 | 0.73 | APLNR (0.65) | HIF1AAPLNRDHFRCYP1A2CYP3A4 | |
| SCHEMBL28124357 | 0.73 | CA1 (0.69) | CA1CA2HIF1ACYP1A2ALDH1A1 | |
| SCHEMBL28123909 | 0.72 | CA1 (0.59) | CA1CA2HIF1AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110446699-A | 2(1H) -quinolinone derivatives | TAISHO PHARMACEUTICAL CO LTD | 2019-11-12 | — | — | CN | disclosed |