Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21639625 | 0.82 | PPARG (0.44) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL28330781 | 0.81 | MEN1 (0.53) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL21674069 | 0.75 | MEN1 (0.47) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL28330802 | 0.73 | KCNH2 (0.58) | — | |
| SCHEMBL7722705 | 0.72 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL7717671 | 0.72 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL21639623 | 0.72 | PTGS1 (0.40) | NPC1RAB9AMEN1KMT2AHSD17B1 | |
| SCHEMBL1702919 | 0.71 | NPC1 (0.74) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL30489855 | 0.71 | NPC1 (0.74) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL23066443 | 0.69 | NSD2 (0.50) | NPC1RAB9AMEN1KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110446699-A | 2(1H) -quinolinone derivatives | TAISHO PHARMACEUTICAL CO LTD | 2019-11-12 | — | — | CN | disclosed |