Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28330975 | 0.81 | NPC1 (0.47) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL21639550 | 0.81 | MAOA (0.52) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL28330802 | 0.77 | KCNH2 (0.58) | — | |
| SCHEMBL1369128 | 0.75 | DAO (0.50) | PKMALDH1A1GAAHPGDKDM4E | |
| SCHEMBL11405554 | 0.75 | LMNA (0.76) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL4669122 | 0.75 | LMNA (0.76) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL23066443 | 0.74 | NSD2 (0.50) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL2808417 | 0.74 | DHODH (0.58) | GFERALDH1A1POLBMAPTGAA | |
| SCHEMBL29415464 | 0.74 | DHODH (0.58) | GFERALDH1A1POLBMAPTGAA | |
| SCHEMBL31423096 | 0.73 | LCK (0.48) | ALDH1A1MAPTGAAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110446699-A | 2(1H) -quinolinone derivatives | TAISHO PHARMACEUTICAL CO LTD | 2019-11-12 | — | — | CN | disclosed |