Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | BRAF | P15056 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21639625 | 0.85 | PPARG (0.44) | PTGS1RAB9AMEN1NPC1KMT2A | |
| SCHEMBL21674069 | 0.82 | MEN1 (0.47) | RAB9AMEN1NPC1KMT2ATYMS | |
| SCHEMBL21639501 | 0.73 | RAB9A (0.51) | RAB9AMEN1NPC1KMT2A | |
| Trifluoroacetic Acid SCHEMBL28330975 | 0.72 | NPC1 (0.47) | RAB9AMEN1NPC1KMT2ACNR2 | |
| SCHEMBL21639644 | 0.68 | CA12 (0.48) | RAB9ANPC1 | |
| SCHEMBL21639579 | 0.67 | APEX1 (0.52) | RAB9AMEN1NPC1KMT2APOLB | |
| SCHEMBL10330656 | 0.65 | GPR17 (0.54) | RAB9AMEN1NPC1KMT2APOLB | |
| SCHEMBL23066443 | 0.64 | NSD2 (0.50) | RAB9AMEN1NPC1KMT2AMAOB | |
| SCHEMBL21674068 | 0.63 | EGFR (0.41) | RAB9AMEN1NPC1KMT2AMAOB | |
| SCHEMBL21639550 | 0.63 | MAOA (0.52) | RAB9AMEN1NPC1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070747-A1 | 2(1H)-QUINOLINONE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2021-03-11 | — | — | US | disclosed |
| EP-3604281-A1 | 2(1H)-QUINOLINONE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2020-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070747-A1 | 2(1H)-QUINOLINONE DERIVATIVE | TOP2A, TOP2B, TOP1 | PTGS1 641/4885BRAF 3711/4885RAB9A 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.