Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28331122 | 1.00 | GPR119 (0.47) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL22147785 | 0.87 | GPR119 (0.48) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL15507141 | 0.84 | KDM4E (0.48) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL4164968 | 0.84 | KDM4E (0.48) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL16459750 | 0.84 | KDM4E (0.48) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL4164966 | 0.84 | KDM4E (0.48) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL28342102 | 0.84 | KDM4E (0.48) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL651769 | 0.84 | ATM (0.46) | GPR119KDM4EPKMATMKDM1A | |
| SCHEMBL22798953 | 0.84 | ATM (0.46) | GPR119KDM4EPKMATMKDM1A | |
| SCHEMBL651751 | 0.84 | ATM (0.46) | GPR119KDM4EPKMATMKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563085-B | Piperidine CXCR7 receptor modulators | 爱杜西亚药品有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-110563717-B | Piperidine CXCR7 receptor modulators | 爱杜西亚药品有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-110563717-A | piperidine CXCR7receptor modulators | 爱杜西亚药品有限公司 | 2019-12-13 | — | — | CN | disclosed |