Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28331434 | 0.87 | THRB (0.54) | SMN1; SMN2MAPTTSHRKDM4EMEN1 | |
| SCHEMBL28878859 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTTSHRKDM4EMEN1 | |
| SCHEMBL28331422 | 0.84 | MAPT (0.50) | SMN1; SMN2MAPTTSHRKDM4EMEN1 | |
| SCHEMBL28331428 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTTSHRKDM4EMEN1 | |
| SCHEMBL28331420 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTTSHRKDM4EMEN1 | |
| SCHEMBL21373574 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTTSHRKDM4EMEN1 | |
| SCHEMBL28331412 | 0.81 | TRPV6 (0.48) | SMN1; SMN2MAPTTSHRKDM4EMEN1 | |
| SCHEMBL28330025 | 0.79 | TSHR (0.64) | SMN1; SMN2MAPTTSHRKDM4EMEN1 | |
| SCHEMBL28331553 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTTSHRKDM4EKMT2A | |
| SCHEMBL21381467 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRKMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494136-A | Cytoprotective compounds and application thereof | ETH ZUERICH | 2019-11-22 | — | — | CN | claimed |
| CN-110494136-A | Cytoprotective compounds and application thereof | ETH ZUERICH | 2019-11-22 | — | — | CN | disclosed |