Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615650 | 0.79 | MMP2 (0.54) | MMP2CA1CA2PKMALDH1A1 | |
| SCHEMBL7619395 | 0.79 | MMP2 (0.54) | MMP2CA1CA2PKMALDH1A1 | |
| SCHEMBL7619389 | 0.79 | MMP2 (0.54) | MMP2CA1CA2PKMALDH1A1 | |
| SCHEMBL7615647 | 0.79 | MMP2 (0.54) | MMP2CA1CA2PKMALDH1A1 | |
| SCHEMBL7615641 | 0.79 | MMP2 (0.54) | MMP2CA1CA2PKMALDH1A1 | |
| SCHEMBL7619393 | 0.79 | MMP2 (0.54) | MMP2CA1CA2PKMALDH1A1 | |
| SCHEMBL10251453 | 0.76 | ALDH1A1 (0.55) | PKMALDH1A1HTTPOLBMEN1 | |
| SCHEMBL12169328 | 0.72 | ALDH1A1 (0.63) | PKMALDH1A1HTTPOLBMEN1 | |
| SCHEMBL20955891 | 0.71 | ALDH1A1 (0.60) | PKMALDH1A1HTTPOLBMEN1 | |
| SCHEMBL18216886 | 0.71 | ALDH1A1 (0.49) | PKMALDH1A1HTTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110383066-B | Compounds, compositions and methods | 戴纳立制药公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-110383066-A | Compound, composition and method | 戴纳立制药公司 | 2019-10-25 | — | — | CN | disclosed |