Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619389 | 1.00 | MMP2 (0.54) | MMP2ALDH1A1PKMHTTPOLB | |
| SCHEMBL7619393 | 1.00 | MMP2 (0.54) | MMP2ALDH1A1PKMHTTPOLB | |
| SCHEMBL7615650 | 0.81 | MMP2 (0.54) | MMP2ALDH1A1PKMHTTPOLB | |
| SCHEMBL7615641 | 0.81 | MMP2 (0.54) | MMP2ALDH1A1PKMHTTPOLB | |
| SCHEMBL7615647 | 0.81 | MMP2 (0.54) | MMP2ALDH1A1PKMHTTPOLB | |
| SCHEMBL9581972 | 0.80 | MAPT (0.43) | ALDH1A1POLBRAB9ALMNAMEN1 | |
| SCHEMBL28331847 | 0.79 | MMP2 (0.51) | MMP2ALDH1A1PKMHTTPOLB | |
| SCHEMBL4940237 | 0.76 | ALDH1A1 (0.64) | ALDH1A1PKMHTTPOLBNPC1 | |
| SCHEMBL7622160 | 0.74 | MMP2 (0.43) | MMP2ALDH1A1PKMHTTPOLB | |
| SCHEMBL7622162 | 0.74 | MMP2 (0.43) | MMP2ALDH1A1PKMHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620225-B1 | Cephalosporin derivatives | BASILEA PHARMACEUTICA AG (CH) | 2002-11-13 | — | — | EP | disclosed |
| US-5523400-A | 3-(PYRROLIDIN-3-YLIDENE=CH-),7-((2-AMINOTHIAZOL-4-YL)HYDROX -IMINOACETYLAMINO-)-3-CEPHEM DERIVATIVES; BROAD SPECTRUM ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1996-06-04 | — | — | US | disclosed |
| EP-0620225-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-10-19 | — | — | EP | disclosed |