Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30363993 | 0.97 | GAA (0.55) | HRH3GAAMAPTHRH4CYP2D6 | |
| SCHEMBL28959605 | 0.84 | POLB (0.52) | HRH3GAAMAPTHRH4CYP2D6 | |
| SCHEMBL22181781 | 0.80 | CA12 (0.71) | GAAMAPTHDAC1HDAC6NOS3 | |
| SCHEMBL31010354 | 0.79 | DRD2 (0.70) | HRH3HRH4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL17221602 | 0.78 | MAPT (0.62) | HRH3GAAMAPTHDAC1HDAC6 | |
| SCHEMBL7627846 | 0.78 | MAPT (0.62) | HRH3GAAMAPTHDAC1HDAC6 | |
| SCHEMBL3397894 | 0.78 | GAA (0.67) | GAAMAPTCYP2D6CYP2C19HDAC1 | |
| SCHEMBL301503 | 0.78 | GAA (0.62) | HRH3GAAMAPTCYP2D6CYP2C19 | |
| SCHEMBL324202 | 0.77 | MAPT (0.61) | GAAMAPTCYP2D6HDAC1HDAC6 | |
| SCHEMBL11201497 | 0.77 | HRH3 (0.94) | HRH3HRH4CYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372703-A | Five-ring heterocycles miazines compound and application thereof | 罗欣生物科技（上海）有限公司 | 2019-10-25 | — | — | CN | disclosed |