Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.49 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.49 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2829562 | 0.99 | GAA (0.53) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4384264 | 0.90 | GAA (0.52) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4378574 | 0.89 | GAA (0.53) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4376221 | 0.88 | GAA (0.52) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2829096 | 0.80 | ALDH1A1 (0.51) | KDM4EMEN1KMT2AALDH1A1L3MBTL3 | |
| SCHEMBL2831500 | 0.77 | KDM4E (0.50) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4377273 | 0.73 | GPR52 (0.44) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL13090047 | 0.72 | KDM4E (0.62) | KDM4EMEN1KMT2AALDH1A1HIF1A | |
| SCHEMBL2829775 | 0.72 | ALDH1A1 (0.54) | KDM4EMEN1KMT2AALDH1A1L3MBTL3 | |
| SCHEMBL11527779 | 0.72 | NR4A1 (0.63) | GAAKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243776-A1 | Substituted piperidines and their use for the treatment of diseases related to the histamine H3 receptor | High Point Pharmaceuticals, LLC (US) | 2010-10-27 | — | — | EP | claimed |
| EP-2243776-A1 | Substituted piperidines and their use for the treatment of diseases related to the histamine H3 receptor | High Point Pharmaceuticals, LLC (US) | 2010-10-27 | — | — | EP | disclosed |