Hexane

Hexane

SCHEMBL28333356

CCCCCC.Cc1ccccc1N(C)C(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TP53 P04637 1/20 0.52
TRPM8 Q7Z2W7 1/20 0.46
CYP3A4 P08684 2/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.42
SIGMAR1 Q99720 1/20 0.41
KMT2A Q03164 1/20 0.41
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
P2RX7 Q99572 1/20 0.41
HSD17B1 P14061 3/20 0.40
HSD17B2 P37059 2/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
NAAA Q02083 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Decane SCHEMBL28489733 0.98 ALDH1A1 (0.55) ALDH1A1TP53TRPM8CYP3A4LMNA
Heptane SCHEMBL28333266 0.98 ALDH1A1 (0.55) ALDH1A1TP53TRPM8CYP3A4LMNA
Octane SCHEMBL28482856 0.98 ALDH1A1 (0.55) ALDH1A1TP53TRPM8CYP3A4LMNA
Undecane SCHEMBL28333290 0.98 ALDH1A1 (0.55) ALDH1A1TP53TRPM8CYP3A4LMNA
Pentane SCHEMBL28488550 0.97 ALDH1A1 (0.49) ALDH1A1TP53TRPM8CYP3A4LMNA
Butane SCHEMBL28335758 0.93 TRPM8 (0.49) ALDH1A1TP53TRPM8CYP3A4LMNA
Hexanoate SCHEMBL28335647 0.92 AKR1B1 (0.47) ALDH1A1TP53KMT2ACES2CES1
Valeric Acid SCHEMBL28481367 0.91 ALDH1A1 (0.45) ALDH1A1TP53TRPM8CYP3A4LMNA
SCHEMBL1029152 0.89 TRPM8 (0.50) ALDH1A1TRPM8LMNASIGMAR1KMT2A
Benzene SCHEMBL28335658 0.89 TRPM8 (0.50) ALDH1A1TRPM8LMNASIGMAR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112020493-B Method for producing urethane and method for producing isocyanate 旭化成株式会社 2023-04-21 CN disclosed
CN-110546135-B Method for producing isocyanate 旭化成株式会社 2021-12-14 CN disclosed
CN-112020493-A Method for producing carbamate and method for producing isocyanate 旭化成株式会社 2020-12-01 CN disclosed
CN-110546135-A Method for producing isocyanate ASAHI CHEMICAL IND 2019-12-06 CN disclosed