Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 11/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28335658 | 1.00 | TRPM8 (0.50) | TRPM8SIGMAR1ALDH1A1HSD17B1HSD17B2 | |
| Cyclohexane SCHEMBL28333261 | 0.94 | LMNA (0.47) | TRPM8SIGMAR1ALDH1A1HSD17B1HSD17B2 | |
| Toluene SCHEMBL28335771 | 0.94 | HSD17B1 (0.50) | TRPM8SIGMAR1ALDH1A1HSD17B1HSD17B2 | |
| Butane SCHEMBL28335758 | 0.92 | TRPM8 (0.49) | TRPM8SIGMAR1ALDH1A1HSD17B1HSD17B2 | |
| Hexane SCHEMBL28333356 | 0.89 | ALDH1A1 (0.52) | TRPM8SIGMAR1ALDH1A1HSD17B1HSD17B2 | |
| Pentane SCHEMBL28488550 | 0.89 | ALDH1A1 (0.49) | TRPM8SIGMAR1ALDH1A1HSD17B1HSD17B2 | |
| Decane SCHEMBL28489733 | 0.88 | ALDH1A1 (0.55) | TRPM8SIGMAR1ALDH1A1HSD17B1HSD17B2 | |
| Octane SCHEMBL28482856 | 0.88 | ALDH1A1 (0.55) | TRPM8SIGMAR1ALDH1A1HSD17B1HSD17B2 | |
| Undecane SCHEMBL28333290 | 0.88 | ALDH1A1 (0.55) | TRPM8SIGMAR1ALDH1A1HSD17B1HSD17B2 | |
| Heptane SCHEMBL28333266 | 0.88 | ALDH1A1 (0.55) | TRPM8SIGMAR1ALDH1A1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877365-A1 | SUBSTITUTED TOLYL AS FUNGICIDES | FMC CORPORATION (US) | 2021-09-15 | — | — | EP | claimed |
| CN-110028607-A | A kind of synthetic method of stereoregular polymethacrylamide | 哈尔滨工程大学 | 2019-07-19 | — | — | CN | claimed |
| CN-109085255-A | A kind of method HPLC method analysis and prepare 3- (N- p-toluenesulfonyl-L- alanyl oxygroup) -5- phenylpyrrole and its enantiomter | 长春百纯和成医药科技有限公司 | 2018-12-25 | — | — | CN | claimed |
| CN-108956808-A | A kind of method that the vertical lactone enantiomter of biacetyl section was analyzed and prepared to HPLC method | 长春百纯和成医药科技有限公司 | 2018-12-07 | — | — | CN | claimed |
| CN-104058991-B | Novel Process For The Preparation Of Amino Acid Derivatives | 优时比制药有限公司 | 2017-04-12 | — | — | CN | claimed |
| US-20250320314-A1 | CHITOSAN COMPOUNDS AND OPTICAL ISOMER SEPARATING AGENT | DAICEL CORPORATION (JP) | 2025-10-16 | — | — | US | disclosed |
| US-12281104-B2 | Process for the production of ethyl 3-amino-1-[(3R,4S)-4-cyanotetrahydropyran-3-yl]pyrazole-4-carboxylate through chiral separation of a racemic mixture | INTERVET INC. (US) | 2025-04-22 | — | — | US | disclosed |
| CN-117538434-A | Detection method of nilaparib intermediate | 苏州正济医药研究有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-117538435-A | Method for detecting nebivolol intermediate isomer | 苏州正济医药研究有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116751148-A | Isomer compound for inhibiting weed seed germination and seedling growth and application thereof | 青海省农林科学院 | 2023-09-15 | — | — | CN | disclosed |
| US-20220220226-A1 | CHITOSAN COMPOUNDS AND OPTICAL ISOMER SEPARATING AGENT | DAICEL CORPORATION (JP) | 2022-07-14 | — | — | US | disclosed |
| US-20220204483-A1 | Process for the Production of Ethyl 3-Amino-1-[(3R,4S)-4-Cyanotetrahydropyran-3-YL]pyrazole-4-Carboxylate Through Chiral Separation of a Racemic Mixture | INTERVET INC. (US) | 2022-06-30 | — | — | US | disclosed |
| US-5017290-A | Chromatography | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0190466-B1 | PROCESS FOR THE PRODUCTION OF N-METHYLCARBAMATES | ENICHEM SYNTHESIS S.p.A. (IT) | 1990-11-28 | — | — | EP | disclosed |
| US-4966694-A | CELLULOSE TRI-BETA-NAPHTHOATE; OPTICAL RESOLUTIONS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| US-4879038-A | Separation agent comprising acyl- or carbamoyl-substituted polysaccharide | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| US-4659845-A | Process for the production of N-methylcarbamates | ENICHEM SINTESI S.P.A. (IT) | 1987-04-21 | — | — | US | disclosed |
| US-4624870-A | AMMONIUM HYDROXIDE-STABILIZED COLLOIDAL SILICA, ORGANOTRIALKOXYSILANE CONDENSATE | GENERAL ELECTRIC COMPANY (US) | 1986-11-25 | — | — | US | disclosed |
| US-4258200-A | REACTION OF FATTY ACID ESTERS AND AMINES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4251667-A | Process for the preparation of aromatic urethanes | ATLANTIC RICHFIELD COMPANY (US) | 1981-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12281104-B2 | Process for the production of ethyl 3-amino-1-[(3R,4S)-4-cyanotetrahydropyran-3-yl]pyrazole-4-carboxylate through chiral separation of a racemic mixture | CYP3A4, CYP4B1, ACMSD | TRPM8 4780/4885SIGMAR1 1200/4885ALDH1A1 457/4885 |
| US-20220204483-A1 | Process for the Production of Ethyl 3-Amino-1-[(3R,4S)-4-Cyanotetrahydropyran-3-YL]pyrazole-4-Carboxylate Through Chiral Separation of a Racemic Mixture | CYP3A4, CYP4B1, ACMSD | TRPM8 4780/4885SIGMAR1 1200/4885ALDH1A1 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.