SCHEMBL28333533

SCHEMBL28333533

NC1(N)C=CC(c2ccccc2-c2ccc(C(=O)O)cc2)=CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 3/20 0.45
RARB P10826 2/20 0.45
RARG P13631 2/20 0.45
MAP4K4 O95819 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
SCN2A Q99250 1/20 0.38
PIM1 P11309 1/20 0.37
RARA P10276 1/20 0.37
NR2E1 Q9Y466 1/20 0.37
GAA P10253 1/20 0.37
PKM P14618 1/20 0.37
NR1H4 Q96RI1 1/20 0.36
TTR P02766 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
PDK2 Q15119 1/20 0.36
PTPRC P08575 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29257684 0.87 ALDH1A1 (0.35)
SCHEMBL30338452 0.87 ALDH1A1 (0.35)
SCHEMBL28731530 0.86 RXRA (0.45) RXRARARBRARGMAP4K4CA12
SCHEMBL29655431 0.85 ALDH1A1 (0.34)
SCHEMBL30570298 0.82 IDO1 (0.31)
SCHEMBL6280912 0.81 MYC (0.41) CA12CA1CA2CA9GAA
SCHEMBL28387227 0.80 MEN1 (0.34) PKMCYP2C9
Urea SCHEMBL28213343 0.77 LMNA (0.35)
SCHEMBL27974316 0.76 ABL1 (0.47) GAA
SCHEMBL27727195 0.76 LIG1 (0.38) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110577474-B Synthesis method and application of Cd (II) complex with three-dimensional porous structure 天津师范大学 2022-05-31 CN claimed
CN-114436817-A Porous hydrogen bond organic skeleton-based fluorescent probe capable of quantitatively detecting hypochlorite and application thereof 福建农林大学 2022-05-06 CN claimed
CN-110577553-B Synthetic method and application of three-dimensional porous complex based on six-core terbium cluster 天津师范大学 2021-09-21 CN claimed
CN-110577553-A Synthetic method and application of three-dimensional porous complex based on six-core terbium cluster 天津师范大学 2019-12-17 CN claimed
CN-110577474-A Synthesis method and application of Cd (II) complex with three-dimensional porous structure 天津师范大学 2019-12-17 CN claimed
CN-114436817-B Porous hydrogen bond organic framework-based fluorescent probe capable of quantitatively detecting hypochlorite and application thereof 福建农林大学 2024-02-20 CN disclosed
CN-110577474-B Synthesis method and application of Cd (II) complex with three-dimensional porous structure 天津师范大学 2022-05-31 CN disclosed
CN-110577474-B Synthesis method and application of Cd (II) complex with three-dimensional porous structure 天津师范大学 2022-05-31 CN disclosed
CN-114436817-A Porous hydrogen bond organic skeleton-based fluorescent probe capable of quantitatively detecting hypochlorite and application thereof 福建农林大学 2022-05-06 CN disclosed
CN-110577553-B Synthetic method and application of three-dimensional porous complex based on six-core terbium cluster 天津师范大学 2021-09-21 CN disclosed
CN-110577553-B Synthetic method and application of three-dimensional porous complex based on six-core terbium cluster 天津师范大学 2021-09-21 CN disclosed
CN-110577553-A Synthetic method and application of three-dimensional porous complex based on six-core terbium cluster 天津师范大学 2019-12-17 CN disclosed
CN-110577553-A Synthetic method and application of three-dimensional porous complex based on six-core terbium cluster 天津师范大学 2019-12-17 CN disclosed
CN-110577474-A Synthesis method and application of Cd (II) complex with three-dimensional porous structure 天津师范大学 2019-12-17 CN disclosed
CN-110577474-A Synthesis method and application of Cd (II) complex with three-dimensional porous structure 天津师范大学 2019-12-17 CN disclosed