Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 16/20 | 0.48 |
| ▸ | PDE4A | P27815 | 14/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31015999 | 0.90 | PDE4B (0.44) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL5797239 | 0.85 | PDE4D (0.49) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL2363529 | 0.76 | PDE4B (0.50) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL6456302 | 0.73 | PDE4B (0.47) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL4594035 | 0.72 | PDE4B (0.45) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL4402862 | 0.72 | PDE4B (0.46) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL1030007 | 0.72 | PDE4B (0.72) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL29723288 | 0.72 | PDE4B (0.72) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7370492 | 0.72 | PDE4B (0.65) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL5796873 | 0.72 | PDE4B (0.52) | PDE4BPDE4DPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085429-B | Aromatic heterocyclic derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2019-12-10 | — | — | CN | disclosed |