Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 12/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.48 |
| ▸ | PDE4A | P27815 | 10/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28334010 | 0.85 | PDE4B (0.48) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL31015999 | 0.81 | PDE4B (0.44) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5797004 | 0.79 | PDE4B (0.44) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5794099 | 0.79 | PDE4D (0.65) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5797196 | 0.78 | PDE4B (0.52) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5794189 | 0.78 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5950136 | 0.77 | MAPT (0.43) | PDE4DPDE4BPDE4APDE4CMAPT | |
| SCHEMBL5796873 | 0.77 | PDE4B (0.52) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL6456302 | 0.76 | PDE4B (0.47) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5797194 | 0.76 | PDE4B (0.52) | PDE4DPDE4BPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006040645-A1 | N-(3,5-DICHLOROPYRIDIN-4-YL)-2,4,5-ALKOXY AND 2,3,4-ALKOXY BENZAMIDE DERIVATIVES AS PDE-IV (PHOPHODIESTERASE TYPE-IV) INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES SUCH AS ASTHMA | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-20 | — | — | WO | disclosed |