Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306823 | 0.88 | KIF11 (0.50) | SERPINE1AURKATPX2KIF11IGF2BP2 | |
| SCHEMBL18293362 | 0.88 | KIF11 (0.50) | SERPINE1AURKATPX2KIF11IGF2BP2 | |
| SCHEMBL28910204 | 0.86 | SERPINE1 (0.49) | SERPINE1AURKATPX2KIF11IGF2BP2 | |
| SCHEMBL9602945 | 0.82 | SERPINE1 (0.47) | SERPINE1AURKATPX2KIF11IGF2BP2 | |
| SCHEMBL29628993 | 0.76 | SCN5A (0.54) | AURKATPX2KIF11IGF2BP2AKR1C2 | |
| SCHEMBL26803468 | 0.76 | ACP1 (0.48) | SERPINE1AURKATPX2KIF11IGF2BP2 | |
| SCHEMBL168125 | 0.75 | KIF11 (0.47) | KIF11MAPTEPHX2 | |
| SCHEMBL27862141 | 0.75 | KIF11 (0.47) | KIF11MAPTEPHX2 | |
| SCHEMBL29699519 | 0.75 | SCN5A (0.46) | SERPINE1AURKATPX2KIF11AKR1C2 | |
| Biphenyl SCHEMBL15610556 | 0.74 | ALDH1A1 (0.60) | MAPTEPHX2NOTUMEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526843-A | Inhibit calcium/calmodulin dependent protein kinase II compound and its application | ACADEMIA SINICA | 2019-12-03 | — | — | CN | disclosed |