Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28146103 | 0.81 | RAB9A (0.51) | RAB9ANPC1POLBGAAGFER | |
| SCHEMBL28333414 | 0.77 | LOXL2 (0.47) | RAB9ANPC1POLBGAAGFER | |
| SCHEMBL27996204 | 0.76 | GFER (0.70) | RAB9ANPC1POLBGAAGFER | |
| SCHEMBL28220130 | 0.74 | GFER (0.66) | RAB9ANPC1POLBGAAGFER | |
| SCHEMBL22221787 | 0.70 | RAB9A (0.69) | RAB9ANPC1POLBGAAGFER | |
| SCHEMBL17080165 | 0.69 | HRH3 (0.64) | LOXL2CYP2A6HRH3ASIC3 | |
| SCHEMBL28938187 | 0.68 | LMNA (0.52) | RAB9ANPC1POLBGAAGFER | |
| SCHEMBL3820711 | 0.68 | GFER (0.72) | RAB9ANPC1POLBGAAGFER | |
| SCHEMBL27402148 | 0.68 | LOXL2 (0.44) | RAB9ANPC1POLBGAAGFER | |
| SCHEMBL27923764 | 0.68 | GFER (0.61) | RAB9ANPC1POLBGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108003151-B | N- hetervaromatic methyl pyrimidinamine compound and the preparation method and application thereof | 湖南化工研究院有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-108003151-A | N- hetervaromatic methyl pyrimidinamine compounds and preparation method and application | 湖南化工研究院有限公司 | 2018-05-08 | — | — | CN | disclosed |