SCHEMBL28334352

SCHEMBL28334352

COS(=O)(=O)c1cccc[n+]1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 5/20 0.39
ACHE P22303 3/20 0.36
TSHR P16473 1/20 0.36
HRH1 P35367 1/20 0.36
PDE4D Q08499 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
KDM4E B2RXH2 2/20 0.35
LMNA P02545 2/20 0.32
HTT P42858 1/20 0.32
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
MAP2K7 O14733 1/20 0.30
GMNN O75496 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
POLB P06746 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28334357 0.76 PSIP1 (0.35) SMN1; SMN2KDM4EHTTAPOBEC3AAPOBEC3G
SCHEMBL2186115 0.75 HDAC8 (0.41) HDAC8ACHETSHRHRH1PDE4D
SCHEMBL13415014 0.75 ACHE (0.42) HDAC8ACHETSHRHRH1PDE4D
SCHEMBL28336459 0.73 PSIP1 (0.33) SMN1; SMN2KDM4ELMNAHTTPOLB
SCHEMBL28336327 0.71 NPC1 (0.39) TSHRSMN1; SMN2KDM4ELMNAHTT
SCHEMBL26107884 0.71 HDAC8 (0.38) HDAC8ACHETSHRHRH1PDE4D
SCHEMBL8002510 0.69 NPSR1 (0.43) HDAC8SMN1; SMN2KDM4ELMNAHTT
SCHEMBL11256315 0.68 NPSR1 (0.39) HDAC8SMN1; SMN2KDM4ELMNAHTT
SCHEMBL11483152 0.68 HDAC8 (0.64) HDAC8SMN1; SMN2KDM4ELMNAHTT
SCHEMBL11421745 0.68 HTR1A (0.43) HDAC8ACHESMN1; SMN2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106661735-B Palladium plating solution and palladium coating film obtained using the same 日本高纯度化学株式会社 2019-12-10 CN claimed
CN-106661735-B Palladium plating solution and palladium coating film obtained using the same 日本高纯度化学株式会社 2019-12-10 CN disclosed