Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 3/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.53 |
| ▸ | BCR | P11274 | 3/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3607576 | 0.83 | NPC1 (0.64) | NPC1RAB9ATP53MAPK1CASP3 | |
| SCHEMBL920933 | 0.83 | ABL1 (0.71) | NPC1RAB9ATP53MAPK1CASP3 | |
| SCHEMBL3743494 | 0.83 | ABL1 (0.71) | NPC1RAB9ATP53MAPK1CASP3 | |
| SCHEMBL30979899 | 0.81 | ABL1 (0.63) | MAPK1SMN1; SMN2ABL1ABCB1BCR | |
| SCHEMBL1514434 | 0.81 | ABL1 (0.63) | MAPK1SMN1; SMN2ABL1ABCB1BCR | |
| SCHEMBL6733562 | 0.80 | CA1 (0.79) | NPC1RAB9ATP53MAPK1CASP3 | |
| SCHEMBL9151672 | 0.80 | CA1 (0.79) | NPC1RAB9ATP53MAPK1CASP3 | |
| SCHEMBL197522 | 0.80 | CA1 (0.79) | NPC1RAB9ATP53MAPK1CASP3 | |
| SCHEMBL12562821 | 0.80 | SLC6A4 (0.45) | ESR2CA12CA1CA9HSD17B1 | |
| SCHEMBL21589900 | 0.79 | ABL1 (0.50) | NPC1RAB9ATP53MAPK1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324596-A | Synthesis method of biaryl compound | 新疆大学 | 2024-07-12 | — | — | CN | disclosed |
| US-9303208-B2 | Liquid crystal compound containing cyclopentyl and difluorometheneoxy linking group, preparation method and application thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-04-05 | — | — | US | disclosed |
| US-20150218449-A1 | LIQUID CRYSTAL COMPOUND CONTAINING CYCLOPENTYL AND DIFLUOROMETHENEOXY LINKING GROUP, PREPARATION METHOD AND APPLICATION THEREOF | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATRIALS CO., LTD. (CN) | 2015-08-06 | — | — | US | disclosed |
| US-20100185019-A1 | CATALYST COMPOSITION AND PROCESS FOR PRODUCING CROSS-COUPLED COMPOUND USING SAME | TOSOH FINECHEM CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| EP-2168680-A1 | CATALYST COMPOSITION AND METHOD FOR PRODUCING CROSS-COUPLING COMPOUND USING THE SAME | Kyoto University (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-7501510-B2 | Thiourea compositions and uses thereof | THE UNIVERSITY OF HONG KONG (CN) | 2009-03-10 | — | — | US | disclosed |
| US-7501510-B2 | Thiourea compositions and uses thereof | THE UNIVERSITY OF HONG KONG (CN) | 2009-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100185019-A1 | CATALYST COMPOSITION AND PROCESS FOR PRODUCING CROSS-COUPLED COMPOUND USING SAME | PYM1, CHRM2, CHRM1 | NPC1 3847/4885RAB9A 1566/4885TP53 2796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.