Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.63 |
| ▸ | BCR | P11274 | 2/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1514434 | 1.00 | ABL1 (0.63) | ABL1ABCB1BCRPTGS1TAAR1 | |
| SCHEMBL10801821 | 0.88 | PTGS1 (0.52) | ABL1ABCB1BCRPTGS1TAAR1 | |
| SCHEMBL15624598 | 0.86 | NFE2L2 (0.59) | ABL1ABCB1BCRPTGS1TAAR1 | |
| SCHEMBL1180429 | 0.85 | ABL1 (0.83) | ABL1ABCB1BCRESR2HDAC4 | |
| SCHEMBL27649742 | 0.81 | ABL1 (0.77) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL792197 | 0.81 | ABL1 (0.77) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL1180412 | 0.81 | ABL1 (0.77) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL2833469 | 0.81 | NPC1 (0.57) | ABL1ABCB1BCRPTGS1ESR2 | |
| SCHEMBL16541913 | 0.81 | KIT (0.58) | PTGS1TAAR1ESR2NFE2L2RELA | |
| SCHEMBL6315143 | 0.80 | PTGS1 (0.49) | ABL1ABCB1BCRPTGS1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246940-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | VORONOI INC. (KR) | 2024-07-25 | — | — | US | claimed |
| CN-118324596-A | Synthesis method of biaryl compound | 新疆大学 | 2024-07-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246940-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | ERBB2, EGFR, ERBB3 | ABL1 5/4885ABCB1 288/4885BCR 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.