SCHEMBL28335148

SCHEMBL28335148

NOSCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 6/20 0.48
NOS3 P29474 1/20 0.46
NOS1 P29475 1/20 0.46
NOS2 P35228 1/20 0.46
AGXT P21549 1/20 0.46
POLB P06746 1/20 0.45
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
PRMT1 Q99873 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MAOB P27338 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CALM1 P0DP23 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8450 0.79 IDO1 (0.44) IDO1NOS3NOS1NOS2POLB
Water SCHEMBL28337532 0.77 IDO1 (0.43) IDO1NOS3NOS1NOS2POLB
SCHEMBL8580874 0.75 IDO1 (0.41) IDO1NOS3NOS1NOS2POLB
SCHEMBL7955699 0.75 IDO1 (0.41) IDO1NOS3NOS1NOS2POLB
SCHEMBL546541 0.75 CYP1A2 (0.42) IDO1NOS3NOS1NOS2POLB
SCHEMBL14081414 0.75 IDO1 (0.46) IDO1NOS3NOS1NOS2POLB
SCHEMBL4194780 0.73 IDO1 (0.40) IDO1NOS3NOS1NOS2POLB
SCHEMBL27634197 0.73 IDO1 (0.40) IDO1NOS3NOS1NOS2POLB
SCHEMBL11585690 0.72 IDO1 (0.48) IDO1NOS3NOS1NOS2CYP1A2
SCHEMBL10666358 0.71 IDO1 (0.39) IDO1NOS3NOS1NOS2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119838022-A Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2025-04-18 CN claimed
CN-118557747-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2024-08-30 CN claimed
CN-118434765-A BCMA monoclonal antibodies and antibody-drug conjugates 杭州多禧生物科技有限公司 2024-08-02 CN claimed
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN claimed
CN-115443134-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2022-12-06 CN claimed
CN-114040779-A Conjugates of cell binding molecules containing branched linkers and cytotoxic agents 杭州多禧生物科技有限公司 2022-02-11 CN claimed
CN-113423430-A Amanitoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2021-09-21 CN claimed
CN-112272669-A Cross-linked pyrrolobenzodiazepine dimer (PBD) derivatives and conjugates thereof 杭州多禧生物科技有限公司 2021-01-26 CN claimed
CN-111093707-A Tubulysin homolog conjugates containing branched linkers 杭州多禧生物科技有限公司 2020-05-01 CN claimed
CN-110621673-A Double-stranded linked cytotoxic drug conjugates 杭州多禧生物科技有限公司 2019-12-27 CN claimed
CN-119838022-A Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2025-04-18 CN disclosed
CN-113423430-B Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2024-12-03 CN disclosed
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN disclosed
CN-115443134-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2022-12-06 CN disclosed
CN-114040779-A Conjugates of cell binding molecules containing branched linkers and cytotoxic agents 杭州多禧生物科技有限公司 2022-02-11 CN disclosed
CN-114040781-A Formulation of conjugate of TUBULYSIN derivative and cell binding molecule 杭州多禧生物科技有限公司 2022-02-11 CN disclosed
CN-113423430-A Amanitoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2021-09-21 CN disclosed
CN-112272669-A Cross-linked pyrrolobenzodiazepine dimer (PBD) derivatives and conjugates thereof 杭州多禧生物科技有限公司 2021-01-26 CN disclosed
CN-111093707-A Tubulysin homolog conjugates containing branched linkers 杭州多禧生物科技有限公司 2020-05-01 CN disclosed
CN-110621673-A Double-stranded linked cytotoxic drug conjugates 杭州多禧生物科技有限公司 2019-12-27 CN disclosed