Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2677344 | 0.86 | MMP14 (0.55) | BCHEPPARGMMP14MMP2USP2 | |
| SCHEMBL2637695 | 0.82 | TP53 (0.47) | BCHEPPARGMMP14TP53ALDH1A1 | |
| SCHEMBL30826512 | 0.81 | LTA4H (0.52) | BCHEPPARGMMP2USP2ALDH1A1 | |
| SCHEMBL11373469 | 0.81 | PPARG (0.47) | BCHEPPARGMMP14MMP2USP2 | |
| SCHEMBL17598200 | 0.81 | MMP14 (0.50) | BCHEPPARGMMP14MMP2FFAR4 | |
| Hydrochloric Acid SCHEMBL6831468 | 0.80 | TP53 (0.46) | BCHEPPARGMMP14TP53ALDH1A1 | |
| SCHEMBL11373428 | 0.80 | PPARG (0.44) | BCHEPPARGMMP14MMP2USP2 | |
| SCHEMBL18073570 | 0.79 | HDAC6 (0.50) | BCHEPPARGMMP14MMP2MAPT | |
| SCHEMBL1007940 | 0.79 | HDAC6 (0.50) | BCHEPPARGMMP14MMP2MAPT | |
| SCHEMBL5170269 | 0.79 | HDAC6 (0.50) | BCHEPPARGMMP14MMP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325516-A | HETEROARYL COMPOUNDS AND THEIR USE | 米尼奥尔克斯治疗有限公司 | 2019-10-11 | — | — | CN | disclosed |