Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 14/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 14/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 14/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 13/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30674384 | 0.89 | MEN1 (0.68) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL1105634 | 0.84 | MEN1 (0.65) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL27565139 | 0.84 | DRD2 (0.62) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL29930745 | 0.83 | MEN1 (0.82) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL1091210 | 0.83 | MEN1 (0.82) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| Hydrochloric Acid SCHEMBL5797212 | 0.82 | MEN1 (0.80) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL28004428 | 0.82 | MEN1 (0.69) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL20148244 | 0.78 | ALDH1A1 (0.70) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL8343391 | 0.78 | CHRM2 (0.68) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL1102038 | 0.77 | CHRM2 (0.70) | CHRM2CHRM4CHRM1CHRM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325516-A | HETEROARYL COMPOUNDS AND THEIR USE | 米尼奥尔克斯治疗有限公司 | 2019-10-11 | — | — | CN | disclosed |