Urethane

Urethane

SCHEMBL28335653

CCCCC(C)CCC(C)CCCC.CCOC(N)=O

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.58
ACE2 Q9BYF1 1/20 0.47
CA2 P00918 4/20 0.42
CA1 P00915 4/20 0.42
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
TP53 P04637 1/20 0.37
SLC15A1 P46059 1/20 0.37
LMNA P02545 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 1/20 0.36
OPRM1 P35372 1/20 0.35
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL28333246 0.91 ALOX15 (0.56) ALOX15ACE2CA2CA1CHRNB2
SCHEMBL6908143 0.82 CA2 (0.44) ALOX15ACE2CA2CA1CHRNB2
Urethane SCHEMBL28879515 0.82 ALOX15 (0.65) ALOX15CA2CA1CHRNB2CHRNB4
Hexane SCHEMBL28879543 0.81 ALOX15 (0.79) ALOX15LMNAHSD17B10ATMMAPT
Decane SCHEMBL28489012 0.79 ALOX15 (0.75) ALOX15TP53LMNAHSD17B10CYP3A4
Tetradecane SCHEMBL28207917 0.79 ALOX15 (0.75) ALOX15TP53LMNAHSD17B10CYP3A4
Undecane SCHEMBL28879525 0.79 ALOX15 (0.75) ALOX15TP53LMNAHSD17B10CYP3A4
Heptane SCHEMBL28335708 0.79 ALOX15 (0.75) ALOX15TP53LMNAHSD17B10CYP3A4
SCHEMBL434247 0.77 KMT2A (0.47) ACE2CA2CA1LMNACYP3A4
Urethane SCHEMBL28091758 0.77 ALOX15 (0.79) ALOX15CHRNB2CHRNB4CHRNA3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110546135-B Method for producing isocyanate 旭化成株式会社 2021-12-14 CN disclosed
CN-112020493-A Method for producing carbamate and method for producing isocyanate 旭化成株式会社 2020-12-01 CN disclosed
CN-110546135-A Method for producing isocyanate ASAHI CHEMICAL IND 2019-12-06 CN disclosed