SCHEMBL6908143

SCHEMBL6908143

CCCCC(C)COC(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.44
CA1 P00915 4/20 0.44
ALOX15 P16050 1/20 0.43
TSHR P16473 2/20 0.41
CYP3A4 P08684 2/20 0.41
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ACE2 Q9BYF1 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
SLC15A1 P46059 1/20 0.38
MAPT P10636 1/20 0.38
FAAH O00519 1/20 0.38
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL224692 0.88 ALOX15 (0.46) CA2CA1ALOX15TSHRCYP3A4
SCHEMBL28656944 0.84 CHRNB2 (0.40) ALOX15TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL28656945 0.84 CHRNB2 (0.40) ALOX15TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL8576738 0.83 CA2 (0.44) CA2CA1TSHRCYP3A4ATM
SCHEMBL8646938 0.83 CA2 (0.44) CA2CA1TSHRCYP3A4ATM
Urethane SCHEMBL28335653 0.82 ALOX15 (0.58) CA2CA1ALOX15TSHRCYP3A4
SCHEMBL28671516 0.82 CA2 (0.42) CA2CA1TSHRCYP3A4ATM
SCHEMBL11821362 0.82 ALDH1A1 (0.50) CA2CA1ALOX15TSHRCYP3A4
SCHEMBL28647763 0.82 ACE2 (0.46) CA2CA1TSHRCYP3A4ATM
Urethane SCHEMBL28333246 0.81 ALOX15 (0.56) CA2CA1ALOX15TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1112120-B1 PROCESS AND CATALYST FOR MAKING DIALKYL CARBONATES CATALYTIC DISTILLATION TECH (US) 2004-10-20 EP disclosed
WO-2002096851-A1 PROCESS AND CATALYST FOR MAKING CARBONATES CATALYTIC DISTILLATION TECHNOLOGIES (US) 2002-12-05 WO disclosed
EP-1112120-A4 PROCESS AND CATALYST FOR MAKING DIALKYL CARBONATES CATALYTIC DISTILLATION TECH (US) 2002-07-03 EP disclosed
US-20020082439-A1 Process and catalyst for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES 2002-06-27 US disclosed
US-6392078-B1 USING AN ORGANOTIN CATALYST CATALYTIC DISTILLATION TECHNOLOGIES 2002-05-21 US disclosed
US-RE37337-E1 DIMETHYL CARBONATE; REACTION OF PRIMARY ALCOHOL, SUCH AS METHANOL, WITH UREA IN PRESENCE OF NOVEL ORGANOTIN CATALYST COMPLEX WITH HIGH BOILING ELECTRON DONOR COMPOUND ACTING AS SOLVENT; CONCURRENT DISTILLATION CATALYTIC DISTILLATION TECHNOLOGIES 2001-08-21 US disclosed
EP-1112120-A1 PROCESS AND CATALYST FOR MAKING DIALKYL CARBONATES Catalytic Distillation Technologies (US) 2001-07-04 EP disclosed
WO-2000012212-A1 PROCESS AND CATALYST FOR MAKING DIALKYL CARBONATES CATALYTIC DISTILLATION TECHNOLOGIES (US) 2000-03-09 WO disclosed
US-6010976-A Catalyst for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES (US) 2000-01-04 US disclosed
US-5902894-A REACTING UREA AND A PRIMARY ALCOHOL IN A REACTION ZONE WITH AN ORGANOTIN COMPOUND AND A HIGH BOILING ELECTRON DONOR ATOM CONTAINING SOLVENT CATALYTIC DISTILLATION TECHNOLOGIES (US) 1999-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020082439-A1 Process and catalyst for making dialkyl carbonates ODC1, ADH1C, DKC1 CA2 131/4885CA1 339/4885ALOX15 2684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.