Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656030 | 0.98 | LMNA (0.30) | LMNAHSD17B10 | |
| SCHEMBL29839935 | 0.85 | — | — | |
| SCHEMBL31734153 | 0.84 | MEN1 (0.40) | LMNAHSD17B10 | |
| SCHEMBL3077229 | 0.83 | LMNA (0.35) | LMNAHSD17B10 | |
| SCHEMBL27696459 | 0.81 | FDPS (0.36) | LMNAHSD17B10 | |
| SCHEMBL27594444 | 0.79 | PAOX (0.39) | LMNAHSD17B10 | |
| SCHEMBL27684735 | 0.79 | PAOX (0.39) | LMNAHSD17B10 | |
| SCHEMBL18131107 | 0.78 | LMNA (0.38) | LMNAHSD17B10 | |
| SCHEMBL27879457 | 0.77 | LMNA (0.34) | LMNAHSD17B10 | |
| SCHEMBL28993854 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751199-A | Mitochondrial protease targeted chimera, preparation method and application | 中国科学院基础医学与肿瘤研究所(筹) | 2023-09-15 | — | — | CN | disclosed |
| CN-114907386-A | HEMTAC small molecule degradation agent and application thereof | 山东大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-112409376-A | Protein degradation targeting chimera based on DCAF15, and preparation method and application thereof | 华东师范大学 | 2021-02-26 | — | — | CN | disclosed |
| CN-110551102-B | ALK covalent inhibitors and uses thereof | 四川大学 | 2021-01-12 | — | — | CN | disclosed |
| CN-110548151-B | Design method of covalent drug | 四川大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-110551102-A | ALK covalent inhibitors and uses thereof | UNIV SICHUAN | 2019-12-10 | — | — | CN | disclosed |
| CN-110548151-A | Design method of covalent drug | UNIV SICHUAN | 2019-12-10 | — | — | CN | disclosed |