Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ODC1 | P11926 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696459 | 0.94 | FDPS (0.36) | LMNAODC1HSD17B10FDPSBLM | |
| SCHEMBL27594444 | 0.92 | PAOX (0.39) | LMNAHSD17B10FDPSBLMPAOX | |
| SCHEMBL27684735 | 0.92 | PAOX (0.39) | LMNAHSD17B10FDPSBLMPAOX | |
| SCHEMBL18131107 | 0.86 | LMNA (0.38) | LMNAHSD17B10FDPSPDE3ARAB9A | |
| SCHEMBL27879457 | 0.85 | LMNA (0.34) | LMNAODC1HSD17B10GAAALOX15 | |
| SCHEMBL28656130 | 0.84 | PAOX (0.46) | LMNAHSD17B10CYP1A2MAPTPMP22 | |
| SCHEMBL28335752 | 0.83 | LMNA (0.31) | LMNAHSD17B10 | |
| SCHEMBL16244342 | 0.83 | LMNA (0.44) | LMNAHSD17B10FDPSRAB9AALOX15 | |
| SCHEMBL27535729 | 0.83 | CYP4F2 (0.40) | LMNAHSD17B10GAAALOX15 | |
| SCHEMBL29839935 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661017-B | Bicyclic or tricyclic heterocyclic compounds | 田边三菱制药株式会社 | 2019-09-24 | — | — | CN | disclosed |
| CN-108778273-A | bicyclic aryl monocyclic β -lactam compounds and methods of use thereof for treating bacterial infections | 默沙东公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-104053661-B | The thienopyrimidines inhibitor of atypical protein kinase C | 癌症研究技术有限公司 | 2018-06-19 | — | — | CN | disclosed |
| CN-106661017-A | novel bicyclic or tricyclic heterocyclic compounds | 田边三菱制药株式会社 | 2017-05-10 | — | — | CN | disclosed |
| CN-103608346-B | As the 7-naphthyridine derivatives of hypoxia inducible factor (HIF) hydroxylase inhibitors | 菲布罗根有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-101679408-B | Bicyclic heterocyclic compounds as FGFR inhibitors | ASTEX THERAPEUTICS LTD. (GB) | 2016-04-27 | — | — | CN | disclosed |
| CN-103145616-B | Nitrogen-containing heteroaryl compounds and the purposes in increase endogenous erythropoietin thereof | FIBROGEN INC. (US) | 2015-09-30 | — | — | CN | disclosed |
| CN-104822267-A | INHIBITORS OF HEPATITIS B VIRUS CONVALENTLY CLOSED CIRCULAR DNA FORMATION AND THEIR METHOD OF USE | BARUCH S BLUMBERG INST | 2015-08-05 | — | — | CN | disclosed |
| CN-102459172-B | Tetracyclic compound | CHUGAI PHARMACEUTICAL CO LTD | 2015-06-24 | — | — | CN | disclosed |
| CN-102977015-B | Nitrogen-containing heteroaryl compounds and their use in increasing endogeneous erythropoietin | FIBROGEN INC | 2015-05-06 | — | — | CN | disclosed |
| CN-101479246-A | Amino-ethyl-amino-aryl (AEAA) compounds and their use | CANCER REC TECH LTD (GB) | 2009-07-08 | — | — | CN | disclosed |
| CN-101460507-A | Thiazolyldihydroindazoles | BOEHRINGER INGELHEIM INT (DE) | 2009-06-17 | — | — | CN | disclosed |
| CN-101400679-A | Spiroindolinone derivatives | HOFFMANN LA ROCHE (CH) | 2009-04-01 | — | — | CN | disclosed |
| CN-101277945-A | Indol-3-yl-carbonyl-piperidine and piperazine derivatives | HOFFMANN LA ROCHE (CH) | 2008-10-01 | — | — | CN | disclosed |
| CN-101115755-A | Pyrazolo-pyrimidine derivatives as MGLUR2 antagonists | HOFFMANN LA ROCHE (CH) | 2008-01-30 | — | — | CN | disclosed |
| CN-101023082-A | Fused pyrimidones useful in the treatment and the prevention of cancer | ASTRAZENECA AB (SE) | 2007-08-22 | — | — | CN | disclosed |
| CN-1849328-A | Novel 14 and 15 membered-ring compounds | GLAXO GROUP LTD (GB) | 2006-10-18 | — | — | CN | disclosed |
| CN-1816527-A | Nitrogen-containing heteroaryl compounds and their use in increasing endogenous erythropoietin | FIBROGEN INC (US) | 2006-08-09 | — | — | CN | disclosed |
| CN-1780835-A | Novel fused heterocycles and uses thereof. | ASTRAZENECA AB (SE) | 2006-05-31 | — | — | CN | disclosed |
| CN-1768040-A | Isoquinoline-5-sulfonic acid amides as inhibitors of AKT (protein kinase B) | LILLY CO ELI (US) | 2006-05-03 | — | — | CN | disclosed |