Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CKS1B | P61024 | 3/20 | 0.33 |
| ▸ | SKP1 | P63208 | 3/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | TEC | P42680 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16003617 | 0.79 | KDM4E (0.43) | HPGDCKS1BSKP1SKP2TSHR | |
| SCHEMBL16003610 | 0.72 | CKS1B (0.58) | CKS1BSKP1SKP2KMT2A | |
| SCHEMBL16340755 | 0.71 | GPR119 (0.35) | HPGDCKS1BSKP1SKP2MEN1 | |
| SCHEMBL28336179 | 0.70 | PDE10A (0.47) | KMT2A | |
| SCHEMBL28684926 | 0.69 | CKS1B (0.65) | CKS1BSKP1SKP2 | |
| SCHEMBL28879588 | 0.69 | PDE10A (0.42) | SCN9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL29117227 | 0.66 | NOTUM (0.55) | CHRM3CHRM4CHRM5CHRM1 | |
| SCHEMBL29117230 | 0.66 | NOTUM (0.55) | CHRM3CHRM4CHRM5CHRM1 | |
| SCHEMBL28379144 | 0.65 | POLB (0.52) | SCN1ASCN2ASCN3ACHRM3MEN1 | |
| SCHEMBL28338234 | 0.64 | ATM (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106957317-B | Novel pyrazole derivatives | 持田制药株式会社 | 2019-12-31 | — | — | CN | disclosed |