Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.47 |
| ▸ | WDR5 | P61964 | 6/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16003607 | 0.79 | PDE10A (0.49) | PDE10AWDR5RPS6KB1AKT1KMT2A | |
| Hydrochloric Acid SCHEMBL16341367 | 0.78 | PDE10A (0.48) | PDE10AWDR5RPS6KB1AKT1KMT2A | |
| SCHEMBL16320654 | 0.77 | PDE10A (0.63) | PDE10AWDR5HPGDS | |
| SCHEMBL16003606 | 0.75 | PDE10A (0.58) | PDE10AHPGDS | |
| SCHEMBL16320993 | 0.73 | PDE10A (0.47) | PDE10AWDR5HPGDSKMO | |
| SCHEMBL28338234 | 0.73 | ATM (0.30) | — | |
| SCHEMBL28335954 | 0.70 | HPGD (0.36) | KMT2A | |
| SCHEMBL15933432 | 0.69 | PDCD1 (0.57) | PDE10AWDR5KMT2A | |
| SCHEMBL18329399 | 0.68 | PDCD1 (0.49) | PDE10AWDR5 | |
| SCHEMBL28879588 | 0.68 | PDE10A (0.42) | PDE10AKMT2AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106957317-B | Novel pyrazole derivatives | 持田制药株式会社 | 2019-12-31 | — | — | CN | disclosed |