SCHEMBL2833604

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2231036	0.84	ESR1 (0.43)	NPC1CA1CA2ESR1TSHR
	SCHEMBL2831955	0.83	NPC1 (0.49)	NPC1CA1CA2CA12CA9
	SCHEMBL2838213	0.82	ESR1 (0.46)	NPC1CA1CA2CA9ESR1
	SCHEMBL22766903	0.81	ESR1 (0.41)	NPC1CA1CA2CA12CA9
	SCHEMBL2834274	0.79	ESR1 (0.51)	NPC1CA1CA2ESR1CYP1A2
	SCHEMBL2168346	0.78	MMP1 (0.44)	NPC1CA1CA2ESR1TSHR
	SCHEMBL2835117	0.77	ESR1 (0.50)	NPC1CA1CA2ESR1CYP1A2
	SCHEMBL4582621	0.77	ESR1 (0.57)	NPC1CA1CA2ESR1TSHR
	SCHEMBL2833607	0.76	NPC1 (0.50)	NPC1CA1CA2CA12CA9
	SCHEMBL2834460	0.76	NPC1 (0.59)	NPC1CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.