Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5120623 | 0.80 | HSD17B10 (0.56) | ELANERAB9AF2PLAUALDH1A1 | |
| SCHEMBL4215088 | 0.78 | TP53 (0.46) | ELANERAB9AF2PLAUALDH1A1 | |
| SCHEMBL28336836 | 0.78 | ELANE (0.41) | ELANERAB9AF2PLAUKDM4E | |
| SCHEMBL11310234 | 0.77 | KDM4E (0.46) | RAB9AALDH1A1KDM4EHPGDHIF1A | |
| SCHEMBL5120296 | 0.76 | ELANE (0.56) | ELANEF2PLAUALDH1A1KDM4E | |
| SCHEMBL5120293 | 0.76 | ELANE (0.56) | ELANEF2PLAU | |
| SCHEMBL9987666 | 0.75 | ELANE (0.55) | ELANEF2PLAU | |
| SCHEMBL517483 | 0.75 | ELANE (0.55) | ELANEF2PLAUALDH1A1KDM4E | |
| SCHEMBL4787612 | 0.74 | NPC1 (0.47) | ELANERAB9AF2PLAUHPGD | |
| SCHEMBL6852832 | 0.73 | ELANE (0.53) | ELANEF2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520422-A | Novel pyridone carboxylic acid derivatives or its salt | WAKUNAGA PHARMA CO LTD | 2019-11-29 | — | — | CN | disclosed |