Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5541713 | 0.85 | LPAR1 (0.49) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL19024635 | 0.82 | L3MBTL1 (0.46) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL27534818 | 0.81 | KMT2A (0.52) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL11263712 | 0.81 | KMT2A (0.49) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL27779762 | 0.81 | KMT2A (0.45) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL8473051 | 0.79 | PTGS2 (0.64) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL15695551 | 0.79 | PTGS1 (0.51) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL362211 | 0.79 | PTGS2 (0.64) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL7885098 | 0.79 | PTGS2 (0.64) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL16811751 | 0.79 | ITGA4 (0.47) | KMT2APOLBHTTNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143170-B | For treating the aromatic compounds of pulmonary fibrosis, liver fibrosis, fibrosis of skin and cardiac fibrosis being substituted | 普罗米蒂克医药SMT有限公司 | 2019-11-08 | — | — | CN | disclosed |