SCHEMBL2833709

SCHEMBL2833709

C#CCCCCOC(=O)c1c(F)cc(F)cc1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.38
SERPINE1 P05121 1/20 0.36
ESR1 P03372 3/20 0.36
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
AKR1C4 P17516 1/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34
AKR1C1 Q04828 1/20 0.34
MAOB P27338 3/20 0.34
MAOA P21397 2/20 0.34
ABCG2 Q9UNQ0 1/20 0.34
PTPN2 P17706 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPN6 P29350 1/20 0.33
PTPN11 Q06124 1/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2832833 0.95 SERPINE1 (0.37) ALOX5SERPINE1ESR1GAAKMT2A
SCHEMBL2832600 0.89 KMT2A (0.40) ALOX5SERPINE1ESR1GAAKMT2A
SCHEMBL2835213 0.87 ESR1 (0.41) ALOX5SERPINE1ESR1TDP1AKR1C4
SCHEMBL2835351 0.85 KMT2A (0.47) ALOX5KMT2ATDP1PTPN2PTPN1
SCHEMBL2833907 0.82 POLB (0.48) ALOX5GAAKMT2ATDP1ABCG2
SCHEMBL2835336 0.82 ESR1 (0.42) ALOX5SERPINE1ESR1AKR1C4AKR1C3
SCHEMBL2835117 0.81 ESR1 (0.50) ALOX5ESR1KMT2ATDP1MAOB
SCHEMBL2833607 0.80 NPC1 (0.50) GAAKMT2AMAOBMAOANPC1
SCHEMBL2835383 0.80 KMT2A (0.48) ESR1KMT2ATDP1NPC1MAPT
SCHEMBL2838398 0.78 POLB (0.49) GAAKMT2ATDP1ABCG2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263268-B2 Ester compound, and non-aqueous electrolyte solution and lithium secondary battery each using the ester compound UBE INDUSTRIES, LTD. (JP) 2012-09-11 US disclosed
EP-2108640-B1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND UBE INDUSTRIES (JP) 2012-07-25 EP disclosed
US-20100119955-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND UBE INDUSTRIES, LTD. (JP) 2010-05-13 US disclosed
EP-2108640-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND Ube Industries, Ltd. (JP) 2009-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100119955-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND CEL, LAGE3, PEF1 ALOX5 2101/4885SERPINE1 4479/4885ESR1 119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.