SCHEMBL2835336

SCHEMBL2835336

C#CCCCOC(=O)c1c(F)cc(F)c(F)c1F

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.42
SERPINE1 P05121 1/20 0.36
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA4 P22748 2/20 0.33
ALOX5 P09917 3/20 0.33
NPC1 O15118 1/20 0.33
TDP2 O95551 1/20 0.32
MAOB P27338 2/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
MAOA P21397 1/20 0.32
AKR1C4 P17516 1/20 0.31
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31
AKR1C1 Q04828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2835213 0.95 ESR1 (0.41) ESR1SERPINE1CA1CA2CA4
SCHEMBL2834415 0.91 MEN1 (0.39) ESR1SERPINE1CA1CA2CA4
SCHEMBL2832833 0.86 SERPINE1 (0.37) ESR1SERPINE1ALOX5NPC1TDP2
SCHEMBL2834274 0.85 ESR1 (0.51) ESR1CA1CA2ALOX5NPC1
SCHEMBL2831955 0.82 NPC1 (0.49) ESR1CA1CA2CA4NPC1
SCHEMBL2833709 0.82 ALOX5 (0.38) ESR1SERPINE1ALOX5NPC1MAOB
SCHEMBL2835117 0.81 ESR1 (0.50) ESR1CA1CA2ALOX5NPC1
SCHEMBL2835383 0.80 KMT2A (0.48) ESR1NPC1TDP2
SCHEMBL2832600 0.76 KMT2A (0.40) ESR1SERPINE1ALOX5NPC1TDP2
SCHEMBL2834449 0.76 ESR1 (0.42) ESR1SERPINE1CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263268-B2 Ester compound, and non-aqueous electrolyte solution and lithium secondary battery each using the ester compound UBE INDUSTRIES, LTD. (JP) 2012-09-11 US disclosed
EP-2108640-B1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND UBE INDUSTRIES (JP) 2012-07-25 EP disclosed
US-20100119955-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND UBE INDUSTRIES, LTD. (JP) 2010-05-13 US disclosed
EP-2108640-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND Ube Industries, Ltd. (JP) 2009-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100119955-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND CEL, LAGE3, PEF1 ESR1 119/4885SERPINE1 4479/4885CA1 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.