SCHEMBL2833727

SCHEMBL2833727

COC(C)(C)CCCC(C)CCN(CCCc1ccc(F)c([Ti](C2=CC=CC2)(C2=CC=CC2)c2c(F)ccc(CCCN(CCC(C)CCCC(C)(C)OC)C(=O)c3ccccc3)c2F)c1F)C(=O)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 2/20 0.33
PTGDR2 Q9Y5Y4 2/20 0.31
LPAR5 Q9H1C0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL267283 0.85
SCHEMBL2836901 0.79 LPAR1 (0.36) LPAR1LPAR5
SCHEMBL2832108 0.79 LPAR1 (0.35) LPAR1LPAR5
SCHEMBL2833657 0.77 MC4R (0.34) LPAR1LPAR5
SCHEMBL3161326 0.76
SCHEMBL2830162 0.75 EGFR (0.40) LPAR1LPAR5
SCHEMBL267282 0.75 ALDH1A1 (0.30)
SCHEMBL2837728 0.73 AGER (0.40)
SCHEMBL2833726 0.71
SCHEMBL2831183 0.71 PPARG (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741005-B2 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
EP-1839853-B1 Planographic printing plate precursor and stack thereof FUJIFILM CORP (JP) 2009-07-08 EP disclosed
US-20070231740-A1 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
EP-1839853-A1 Planographic printing plate precursor and stack thereof FUJIFILM Corporation (JP) 2007-10-03 EP disclosed