SCHEMBL2833657

SCHEMBL2833657

CCCC(C)(C)C(=O)N(CCCc1ccc(F)c([Ti](C2=CC=CC2)(C2=CC=CC2)c2c(F)ccc(CCCN(Cc3ccccc3)C(=O)C(C)(C)CCC)c2F)c1F)Cc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MC4R P32245 9/20 0.34
MC3R P41968 8/20 0.34
MC5R P33032 7/20 0.34
LPAR1 Q92633 3/20 0.33
RIPK1 Q13546 3/20 0.33
LPAR5 Q9H1C0 2/20 0.32
CNR2 P34972 1/20 0.32
PKM P14618 2/20 0.31
LTB4R2 Q9NPC1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9800261 0.85 RIPK1 (0.37) RIPK1
SCHEMBL2831183 0.84 PPARG (0.30)
SCHEMBL482766 0.83 MLYCD (0.33) RIPK1
SCHEMBL482535 0.81 RIPK1 (0.38) RIPK1
SCHEMBL9800169 0.81 RIPK1 (0.35) RIPK1
SCHEMBL5179845 0.80 MLYCD (0.34)
SCHEMBL2833652 0.78 TRPM8 (0.35) RIPK1
SCHEMBL2836901 0.78 LPAR1 (0.36) LPAR1LPAR5LTB4R2
SCHEMBL2832108 0.77 LPAR1 (0.35) LPAR1LPAR5LTB4R2
SCHEMBL2833727 0.77 LPAR1 (0.33) LPAR1LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741005-B2 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
EP-1839853-B1 Planographic printing plate precursor and stack thereof FUJIFILM CORP (JP) 2009-07-08 EP disclosed
US-20070231740-A1 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
EP-1839853-A1 Planographic printing plate precursor and stack thereof FUJIFILM Corporation (JP) 2007-10-03 EP disclosed