Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466907 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EGLASMN1; SMN2 | |
| SCHEMBL19231298 | 0.79 | HTT (0.46) | ALDH1A1HPGDGLAMEN1KMT2A | |
| SCHEMBL28337469 | 0.79 | HSD17B10 (0.40) | ALDH1A1HPGDKDM4EGLASMN1; SMN2 | |
| SCHEMBL30139983 | 0.79 | HSD17B10 (0.40) | ALDH1A1HPGDKDM4EGLASMN1; SMN2 | |
| SCHEMBL29779469 | 0.79 | HTT (0.46) | ALDH1A1HPGDGLAMEN1KMT2A | |
| SCHEMBL29273663 | 0.79 | HSD17B10 (0.40) | ALDH1A1HPGDKDM4EGLASMN1; SMN2 | |
| SCHEMBL30868890 | 0.78 | FGFR1 (0.46) | ALDH1A1HPGDKDM4EGLAMEN1 | |
| SCHEMBL11999832 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EGLAMEN1 | |
| SCHEMBL19200298 | 0.78 | FGFR1 (0.46) | ALDH1A1HPGDKDM4EGLAMEN1 | |
| SCHEMBL29258490 | 0.77 | LMNA (0.41) | ALDH1A1HPGDKDM4EGLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119663301-A | Preparation method and application of C3-cyanoalkyl substituted quinoxalinone | 安阳工学院 | 2025-03-21 | — | — | CN | disclosed |
| CN-118345387-A | Method for synthesizing silicon-based substituted quinoxalinone compound by electrochemical Minisci reaction | 江苏食品药品职业技术学院 | 2024-07-16 | — | — | CN | disclosed |
| CN-114524773-B | Synthesis method of aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-118047727-A | Method for preparing quinoxaline-2, 3-diketone compound by virtue of regioselective photocatalytic oxidation | 浙江工业大学台州研究院 | 2024-05-17 | — | — | CN | disclosed |
| CN-114920706-B | Method for preparing 3-acyl-quinoxaline-2 (1H) -ketone by ball milling method | 新乡市润宇新材料科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-113956208-B | Aryl heterocyclic derivative and synthesis method thereof | 郑州大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-116410147-A | Method for rapidly preparing 3-acyl-quinoxaline-2 (1H) -ketone under ball milling condition | 新乡市润宇新材料科技有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-116120246-A | 3-butyl-2 (1H) quinoxalinone compound and preparation method thereof | 常州大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-114195792-B | Synthesis method of 1,2, 3-triazole quinoxalinone derivative | 常州大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-113774411-B | Method for electrochemically synthesizing aryl-substituted quinoxaline (ketone) derivative | 浙江工业大学 | 2022-12-27 | — | — | CN | disclosed |
| CN-113956208-A | Aryl heterocyclic derivative and synthetic method thereof | 郑州大学 | 2022-01-21 | — | — | CN | disclosed |
| CN-113774411-A | Method for electrochemically synthesizing aryl-substituted quinoxaline (ketone) derivative | 浙江工业大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-113264923-A | Synthesis method of 3-gamma-lactam/acylamino alkyl substituted quinoxalinone derivative | 浙江工业大学 | 2021-08-17 | — | — | CN | disclosed |
| CN-108976174-B | Preparation method of 3-trifluoromethyl quinoxalinone compound | 河北工业大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-108752325-B | Preparation method of 3-oxyalkyl quinoxaline-2 (1H) -ketone compound | 曲阜师范大学 | 2021-03-23 | — | — | CN | disclosed |
| CN-107973755-B | Preparation method of 3-acetamido quinoxalinone derivative | 滨州学院 | 2020-12-29 | — | — | CN | disclosed |
| CN-108033922-B | Preparation method of 3-acyl quinoxalinone derivative | 河南工业大学 | 2020-11-06 | — | — | CN | disclosed |
| CN-111848628-A | Imidazo [1,5-a ] quinoxaline-4 (5H) -ketone compound synthesized by metal-free catalysis and preparation method thereof | 郑州大学 | 2020-10-30 | — | — | CN | disclosed |
| CN-111635370-A | Photocatalytic preparation method of 3-alkyl quinoxalinone derivative | 河南工业大学 | 2020-09-08 | — | — | CN | disclosed |
| CN-110590684-A | Synthetic method of 3-alkylthio substituted quinoxalinone derivative | 浙江工业大学 | 2019-12-20 | — | — | CN | disclosed |