SCHEMBL29466907

SCHEMBL29466907

Cc1cc2ncc(=O)n(C)c2cc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
HPGD P15428 3/20 0.53
KDM4E B2RXH2 3/20 0.53
GLA P06280 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 2/20 0.41
CYP1A2 P05177 4/20 0.40
CASP1 P29466 3/20 0.40
CASP7 P55210 3/20 0.40
HSD17B10 Q99714 3/20 0.40
CYP2D6 P10635 1/20 0.40
GAA P10253 1/20 0.40
POLB P06746 1/20 0.39
USP2 O75604 2/20 0.38
CYP2C19 P33261 1/20 0.38
NQO2 P16083 1/20 0.38
TP53 P04637 1/20 0.36
GGPS1 O95749 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28337409 1.00 ALDH1A1 (0.53) ALDH1A1HPGDKDM4EGLASMN1; SMN2
SCHEMBL19231298 0.79 HTT (0.46) ALDH1A1HPGDGLAMEN1KMT2A
SCHEMBL28337469 0.79 HSD17B10 (0.40) ALDH1A1HPGDKDM4EGLASMN1; SMN2
SCHEMBL30139983 0.79 HSD17B10 (0.40) ALDH1A1HPGDKDM4EGLASMN1; SMN2
SCHEMBL29779469 0.79 HTT (0.46) ALDH1A1HPGDGLAMEN1KMT2A
SCHEMBL29273663 0.79 HSD17B10 (0.40) ALDH1A1HPGDKDM4EGLASMN1; SMN2
SCHEMBL30868890 0.78 FGFR1 (0.46) ALDH1A1HPGDKDM4EGLAMEN1
SCHEMBL11999832 0.78 ALDH1A1 (0.44) ALDH1A1HPGDKDM4EGLAMEN1
SCHEMBL19200298 0.78 FGFR1 (0.46) ALDH1A1HPGDKDM4EGLAMEN1
SCHEMBL29258490 0.77 LMNA (0.41) ALDH1A1HPGDKDM4EGLASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684221-A Synthesis method and application of C-3-hydroxyfluoroalkyl substituted quinoxalinone derivative 天津科技大学 2025-03-25 CN claimed
CN-119913525-A Electrochemical synthesis method of 3-aryl quinoxalinone compound 新疆大学 2025-05-02 CN disclosed
CN-119684221-A Synthesis method and application of C-3-hydroxyfluoroalkyl substituted quinoxalinone derivative 天津科技大学 2025-03-25 CN disclosed
CN-118994039-A Method for selectively synthesizing nitrogen-containing heterocyclic compound 浙江树人学院 2024-11-22 CN disclosed
CN-116120246-B 3-Butyl-2 (1H) quinoxalinone compound and preparation method thereof 常州大学 2024-11-19 CN disclosed
CN-118373779-A Preparation method of 1-difluoromethyl-3-heterocyclic bicyclo [1.1.1] pentane 浙江工业大学 2024-07-23 CN disclosed
CN-118345387-A Method for synthesizing silicon-based substituted quinoxalinone compound by electrochemical Minisci reaction 江苏食品药品职业技术学院 2024-07-16 CN disclosed
CN-114524773-B Synthesis method of aryl quinoxaline compound promoted by mechanical force 浙江工业大学 2024-05-28 CN disclosed
CN-118047727-A Method for preparing quinoxaline-2, 3-diketone compound by virtue of regioselective photocatalytic oxidation 浙江工业大学台州研究院 2024-05-17 CN disclosed
CN-114920706-B Method for preparing 3-acyl-quinoxaline-2 (1H) -ketone by ball milling method 新乡市润宇新材料科技有限公司 2023-10-20 CN disclosed
CN-116410147-A Method for rapidly preparing 3-acyl-quinoxaline-2 (1H) -ketone under ball milling condition 新乡市润宇新材料科技有限公司 2023-07-11 CN disclosed
CN-116120246-A 3-butyl-2 (1H) quinoxalinone compound and preparation method thereof 常州大学 2023-05-16 CN disclosed
CN-114195792-B Synthesis method of 1,2, 3-triazole quinoxalinone derivative 常州大学 2023-01-17 CN disclosed
CN-113774411-B Method for electrochemically synthesizing aryl-substituted quinoxaline (ketone) derivative 浙江工业大学 2022-12-27 CN disclosed
CN-115385863-A Synthetic method of 3- (diethoxymethyl) -1-alkyl-2 (1H) -quinoxalinone derivative 河南师范大学 2022-11-25 CN disclosed
CN-114920706-A Method for preparing 3-acyl-quinoxaline-2 (1H) -ketone by ball milling method 新乡市润宇新材料科技有限公司 2022-08-19 CN disclosed
CN-113264923-B Synthesis method of 3-gamma-lactam/acylamino alkyl substituted quinoxalinone derivative 浙江工业大学 2022-07-08 CN disclosed
CN-110483421-B Preparation method of quinoxalinone derivative 沈阳师范大学 2022-06-10 CN disclosed
CN-114524773-A Method for synthesizing aryl quinoxaline compound promoted by mechanical force 浙江工业大学 2022-05-24 CN disclosed
CN-114195792-A Synthesis method of 1,2, 3-triazole quinoxalinone derivative 常州大学 2022-03-18 CN disclosed