Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21877204 | 0.86 | APLNR (0.32) | MEN1KMT2AAPLNRCA1CA2 | |
| SCHEMBL28673657 | 0.85 | APLNR (0.31) | APLNR | |
| SCHEMBL28337567 | 0.85 | NOS1 (0.32) | APLNRNOS1NOS3NOS2 | |
| SCHEMBL1696184 | 0.82 | MEN1 (0.38) | MEN1KMT2AAPLNRCA1CA2 | |
| SCHEMBL7561602 | 0.80 | MEN1 (0.42) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL21877017 | 0.80 | CA12 (0.33) | TSHRAPLNRTDP1CA1CA2 | |
| SCHEMBL12171728 | 0.80 | MEN1 (0.35) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL13477861 | 0.79 | MEN1 (0.38) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL20253994 | 0.79 | ALDH1A1 (0.41) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL18105903 | 0.79 | ALDH1A1 (0.41) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980327-A | Specific coupling of antibodies | 杭州多禧生物科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-116194084-A | Cleavable lipid compounds, compositions containing the same and uses thereof | 赛诺菲巴斯德有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-116143678-A | Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-115942958-A | Phthalocyanine dye compounds, conjugates and methods of use thereof | 乐天医药生技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-110099682-B | Coupled connector, cell binding molecule-drug conjugate containing same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115300640-A | Novel linkers and their use for specific coupling of drugs and biomolecules | 杭州多禧生物科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-115181164-A | Derivatives of amatoxins and their coupling to cell binding molecules | 杭州多禧生物科技有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-109689107-B | Derivatives of amatoxins and their coupling to cell binding molecules | 杭州多禧生物科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-108289964-B | Novel linkers and their use for specific coupling of drugs and biomolecules | 杭州多禧生物科技有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114040778-A | Cell binding molecule-Tubulysin derivative conjugate and preparation method thereof | 杭州多禧生物科技有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-113382754-A | Compounds, compositions, methods and uses for treating cancer and immune disorders | IL-2RX公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-113195487-A | 2, 3-diaminosuccinyl conjugate linkers | 杭州多禧生物科技有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-112272669-A | Cross-linked pyrrolobenzodiazepine dimer (PBD) derivatives and conjugates thereof | 杭州多禧生物科技有限公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-105524053-B | Tetrahydrobenzothiophene compounds | 广东东阳光药业有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-110621673-A | Double-stranded linked cytotoxic drug conjugates | 杭州多禧生物科技有限公司 | 2019-12-27 | — | — | CN | disclosed |