SCHEMBL28337607

SCHEMBL28337607

NC(=O)OC(C=O)Cc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.54
PPARG P37231 5/20 0.53
PPARA Q07869 3/20 0.53
LTA4H P09960 3/20 0.53
LAP3 P28838 1/20 0.53
FFAR1 O14842 1/20 0.52
FFAR4 Q5NUL3 1/20 0.52
ALOX5 P09917 1/20 0.49
MAOB P27338 1/20 0.49
NR4A1 P22736 1/20 0.49
NR4A2 P43354 1/20 0.49
NR4A3 Q92570 1/20 0.49
PPARD Q03181 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28337605 1.00 PARP10 (0.54) PARP10PPARGPPARALTA4HLAP3
SCHEMBL14762630 0.87 SRR (0.46)
SCHEMBL28540100 0.87 SRR (0.46)
SCHEMBL7296959 0.87 SRR (0.46)
SCHEMBL28978081 0.83 PPARG (0.48) PPARGPPARALTA4HLAP3FFAR1
SCHEMBL9341975 0.83 PPARG (0.48) PPARGPPARALTA4HLAP3FFAR1
SCHEMBL28570428 0.79 LDHA (0.53) PARP10PPARGPPARA
SCHEMBL4047593 0.79 PPARA (0.60) PARP10PPARGPPARALTA4HLAP3
SCHEMBL4047589 0.79 PPARA (0.60) PARP10PPARGPPARALTA4HLAP3
SCHEMBL28303037 0.78 PARP10 (0.52) PARP10PPARGPPARALTA4HLAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117980327-A Specific coupling of antibodies 杭州多禧生物科技有限公司 2024-05-03 CN disclosed
CN-116143678-A Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof 杭州多禧生物科技有限公司 2023-05-23 CN disclosed
CN-113195487-A 2, 3-diaminosuccinyl conjugate linkers 杭州多禧生物科技有限公司 2021-07-30 CN disclosed
CN-110621673-A Double-stranded linked cytotoxic drug conjugates 杭州多禧生物科技有限公司 2019-12-27 CN disclosed