Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.60 |
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | LAP3 | P28838 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047589 | 1.00 | PPARA (0.60) | PPARAPPARGPPARDPARP10LTA4H | |
| SCHEMBL28337607 | 0.79 | PARP10 (0.54) | PPARAPPARGPPARDPARP10LTA4H | |
| SCHEMBL28337605 | 0.79 | PARP10 (0.54) | PPARAPPARGPPARDPARP10LTA4H | |
| SCHEMBL28303037 | 0.78 | PARP10 (0.52) | PPARAPPARGPARP10LTA4HLAP3 | |
| SCHEMBL3787413 | 0.78 | PPARG (0.56) | PPARAPPARGPARP10LTA4HLAP3 | |
| SCHEMBL3787409 | 0.78 | PPARG (0.56) | PPARAPPARGPARP10LTA4HLAP3 | |
| SCHEMBL288435 | 0.78 | PPARA (0.74) | PPARAPPARGPPARDLTA4HLAP3 | |
| SCHEMBL8391536 | 0.76 | LTA4H (0.63) | PPARAPPARGPARP10LTA4HLAP3 | |
| SCHEMBL8391534 | 0.76 | LTA4H (0.63) | PPARAPPARGPARP10LTA4HLAP3 | |
| SCHEMBL5309440 | 0.76 | PPARG (0.71) | PPARAPPARGPPARDLTA4HFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719773-B1 | FUSED HETEROTETRACYCLIC COMPOUNDS AND USE TEHREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC (JP) | 2009-04-15 | — | — | EP | disclosed |