Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28337676 | 0.83 | HSD17B10 (0.35) | PRNPKMT2AMEN1USP2MAPT | |
| SCHEMBL9646427 | 0.79 | KDM4E (0.48) | KMT2AMEN1LMNAHTTMAPT | |
| SCHEMBL18263212 | 0.79 | LMNA (0.50) | KMT2AMEN1LMNAHTTUSP2 | |
| SCHEMBL7119836 | 0.76 | HSD17B10 (0.52) | KMT2AMEN1LMNAMAPTHSD17B10 | |
| SCHEMBL11411081 | 0.76 | KMT2A (0.38) | PRNPKMT2AMEN1NPC1RAB9A | |
| SCHEMBL31389161 | 0.76 | KMT2A (0.38) | PRNPKMT2AMEN1NPC1RAB9A | |
| SCHEMBL57100 | 0.74 | KMT2A (0.44) | KMT2AMEN1NPC1LMNAHTT | |
| SCHEMBL30410456 | 0.74 | THRB (0.40) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL18272061 | 0.74 | ELANE (0.47) | — | |
| SCHEMBL1728306 | 0.73 | MAPK1 (0.47) | KMT2AMEN1USP2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108416-B | Preparation method of 1, 2-dicyclopropylethylphenol and optical isomer thereof | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |