Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132494 | 0.77 | ESR2 (0.59) | MAOAKDRADORA2AADORA1ESR1 | |
| SCHEMBL23738688 | 0.75 | CYP2A6 (0.41) | MAOAKDRADORA2AADORA1ESR1 | |
| SCHEMBL11546612 | 0.75 | MAOA (0.40) | MAOAKDRADORA2AADORA1ESR1 | |
| SCHEMBL15679182 | 0.75 | MAPK1 (0.41) | MAOAKDRADORA2AADORA1ESR1 | |
| SCHEMBL6522700 | 0.73 | MTNR1A (0.43) | MAOAKDRADORA2AADORA1ESR1 | |
| Fluorene SCHEMBL473154 | 0.72 | MAOA (0.56) | MAOAKDRADORA2AADORA1SRD5A2 | |
| SCHEMBL28907906 | 0.71 | MAOA (0.62) | MAOASRD5A2BCHECES1LMNA | |
| SCHEMBL29960895 | 0.71 | KDR (0.39) | MAOAKDRADORA2AADORA1ESR1 | |
| SCHEMBL23955997 | 0.71 | MAOA (0.36) | MAOAKDRADORA2AADORA1ESR1 | |
| SCHEMBL20528880 | 0.71 | MAOA (0.36) | MAOAKDRADORA2AADORA1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110650978-B | Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-110650978-A | Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2020-01-03 | — | — | CN | disclosed |