Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834363 | 0.89 | BRD9 (0.34) | NPC1HPGDRAB9AL3MBTL1BRD9 | |
| SCHEMBL2834947 | 0.86 | DDX3X (0.36) | NPC1HPGDRAB9AL3MBTL1BRD9 | |
| SCHEMBL2841614 | 0.86 | KDM4E (0.32) | NPC1HPGDRAB9AL3MBTL1BRD9 | |
| SCHEMBL2837070 | 0.85 | ESR1 (0.40) | NPC1HPGDRAB9AL3MBTL1 | |
| SCHEMBL2834359 | 0.85 | NPC1 (0.39) | NPC1HPGDRAB9AL3MBTL1 | |
| SCHEMBL2833844 | 0.85 | NPC1 (0.39) | NPC1HPGDRAB9AL3MBTL1 | |
| SCHEMBL2836109 | 0.85 | KMT2A (0.40) | NPC1HPGDRAB9ABRD9 | |
| SCHEMBL2842393 | 0.85 | XPO1 (0.32) | NPC1HPGDRAB9AL3MBTL1BRD9 | |
| SCHEMBL1573784 | 0.85 | NPC1 (0.39) | NPC1HPGDRAB9AL3MBTL1 | |
| SCHEMBL2836987 | 0.85 | CNR1 (0.35) | NPC1HPGDRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754880-B2 | Uracils having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2010-07-13 | — | — | US | claimed |
| US-20060025591-A1 | New uracils having a herbicidal activity | ISEM S.R.L. (IT) | 2006-02-02 | — | — | US | claimed |
| US-7754880-B2 | Uracils having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2010-07-13 | — | — | US | disclosed |
| US-20060025591-A1 | New uracils having a herbicidal activity | ISEM S.R.L. (IT) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025591-A1 | New uracils having a herbicidal activity | UNG, DDT, UMPS | NPC1 4643/4885HPGD 2001/4885RAB9A 2151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.