SCHEMBL2833864

SCHEMBL2833864

CCCCCCCC/C=C\CCCCCCCC(=O)O[C@@H](CO)COC(=O)C=Cc1ccc(O)c(OC)c1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PRKCA P17252 2/20 0.57
▸ PRKCE Q02156 1/20 0.57
▸ PRKCQ Q04759 1/20 0.57
▸ PRKCD Q05655 1/20 0.57
▸ PPARG P37231 1/20 0.53
▸ MAOB P27338 1/20 0.53
▸ HTR1A P08908 1/20 0.52
▸ TRPV1 Q8NER1 3/20 0.49
▸ TOP2A P11388 1/20 0.49
▸ S1PR1 P21453 1/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ TP53 P04637 1/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ CYP2D6 P10635 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ HPGD P15428 1/20 0.47
▸ MTOR P42345 1/20 0.47
▸ KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2832869 0.96 MAOB (0.55) PRKCAPRKCEPRKCQPRKCDPPARG
SCHEMBL2837789 0.90 PPARG (0.55) PRKCAPRKCEPRKCQPRKCDPPARG
SCHEMBL7701163 0.88 PRKCA (0.53) PRKCAPRKCEPRKCQPRKCDHTR1A
SCHEMBL2829889 0.87 MAOB (0.55) PPARGMAOBHTR1ATRPV1TOP2A
Oleic Acid SCHEMBL27768091 0.84 HTR1A (0.54) PPARGMAOBHTR1ATRPV1MEN1
SCHEMBL12920818 0.84 TRPV1 (0.52) PRKCAPRKCEPRKCQPRKCDPPARG
SCHEMBL7700996 0.83 PRKCE (0.53) PRKCAPRKCEPRKCQPRKCDHTR1A
SCHEMBL9063847 0.83 HTR1A (0.61) PPARGMAOBHTR1ATRPV1TOP2A
SCHEMBL2832034 0.82 MAOB (0.66) PRKCEPRKCQPRKCDMAOBTOP2A
SCHEMBL4666017 0.82 HTR1A (0.52) PPARGHTR1ATRPV1TOP2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8357353-B2 Compositions comprising a UV-absorbing chromophore BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2013-01-22 — — US disclosed
US-20100215600-A1 Compositions comprising a UV-absorbing chromophore BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2010-08-26 — — US disclosed
US-7727514-B2 Compositions comprising a UV-absorbing chromophore BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2010-06-01 — — US disclosed
US-7572610-B2 Methods of making compositions comprising a UV-Absorbing chromophore BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2009-08-11 — — US disclosed
US-20070077214-A1 COMPOSITIONS COMPRISING A UV-ABSORBING CHROMOPHORE BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2007-04-05 — — US disclosed
US-20070077636-A1 METHODS OF MAKING COMPOSITIONS COMPRISING A UV-ABSORBING CHROMOPHORE BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2007-04-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070077214-A1 COMPOSITIONS COMPRISING A UV-ABSORBING CHROMOPHORE CRY2, ERCC4, CCNB2 PRKCA 4639/4885PRKCE 4301/4885PRKCQ 3958/4885
US-20100215600-A1 Compositions comprising a UV-absorbing chromophore CRY2, ERCC4, CCNB2 PRKCA 4639/4885PRKCE 4301/4885PRKCQ 3958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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